Abstract
Two recent studies in Molecular Cell (Lan et al., 2007; Rudolph et al., 2007) implicate histone demethylation by LSD1 in the regulation of boundaries between silenced and active chromatin domains in both fission yeast and flies, but by distinct mechanisms.
MeSH terms
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Animals
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Chromatin / enzymology*
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Chromatin / genetics*
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Drosophila Proteins / genetics*
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Drosophila Proteins / metabolism*
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Drosophila melanogaster / enzymology*
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Drosophila melanogaster / genetics*
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Euchromatin / enzymology
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Euchromatin / genetics
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Genes, Fungal
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Genes, Insect
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Heterochromatin / enzymology
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Heterochromatin / genetics
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Histones / metabolism
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Models, Biological
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Oxidoreductases, N-Demethylating / genetics*
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Oxidoreductases, N-Demethylating / metabolism*
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Schizosaccharomyces / enzymology*
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Schizosaccharomyces / genetics*
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Schizosaccharomyces pombe Proteins / genetics
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Schizosaccharomyces pombe Proteins / metabolism
Substances
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Chromatin
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Drosophila Proteins
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Euchromatin
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Heterochromatin
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Histones
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Schizosaccharomyces pombe Proteins
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Oxidoreductases, N-Demethylating