Chromosome congression: the kinesin-8-step path to alignment

Curr Biol. 2007 May 1;17(9):R326-8. doi: 10.1016/j.cub.2007.03.013.

Abstract

During mitosis, chromosomes must become aligned at the equator of the mitotic spindle before segregation. Recent work suggests that a kinesin-8 motor uses a unique combination of activities to regulate this process.

Publication types

  • Review
  • Comment

MeSH terms

  • Anaphase / physiology*
  • Chromosome Segregation / physiology*
  • Humans
  • Kinesins / metabolism*
  • Kinetochores / metabolism
  • Microtubules / metabolism
  • Molecular Motor Proteins / metabolism*

Substances

  • Molecular Motor Proteins
  • KIF18A protein, human
  • Kinesins