Sleep-dependent memory consolidation and reconsolidation

Sleep Med. 2007 Jun;8(4):331-43. doi: 10.1016/j.sleep.2007.03.011. Epub 2007 Apr 30.


Molecular, cellular, and systems-level processes convert initial, labile memory representations into more permanent ones, available for continued reactivation and recall over extended periods of time. These processes of memory consolidation and reconsolidation are not all-or-none phenomena, but rather a continuing series of biological adjustments that enhance both the efficiency and utility of stored memories over time. In this chapter, we review the role of sleep in supporting these disparate but related processes.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Brain / anatomy & histology*
  • Brain / metabolism
  • Discrimination, Psychological
  • Humans
  • Learning
  • Magnetic Resonance Imaging
  • Memory / physiology*
  • Neuronal Plasticity / physiology
  • Psychomotor Performance / physiology
  • Sleep / physiology*
  • Sleep, REM / physiology
  • Visual Perception / physiology