Nutritional deficiencies in celiac disease

Gastroenterol Clin North Am. 2007 Mar;36(1):93-108, vi. doi: 10.1016/j.gtc.2007.01.006.


Celiac disease is characterized by small bowel enteropathy, precipitated in genetically susceptible individuals by the ingestion of "gluten," which is a term used to encompass the storage proteins of wheat, rye, and barley. Although the intestine heals with removal of gluten from the diet, the intolerance is permanent and the damage recurs if gluten is reintroduced. This damage causes a wide variety of consequence including maldigestion and malabsorption, resulting in the characteristic, although not universal, features of malnutrition. This article examines recent advances in the understanding of the spectrum of celiac disease, illustrates the impact of celiac disease on nutrition, and describes approaches to the management of the disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Celiac Disease / complications*
  • Celiac Disease / diagnosis
  • Celiac Disease / diet therapy
  • Celiac Disease / epidemiology
  • Diet, Protein-Restricted
  • Female
  • Glutens / adverse effects
  • Humans
  • Malabsorption Syndromes / diagnosis
  • Malabsorption Syndromes / diet therapy
  • Malabsorption Syndromes / epidemiology
  • Malabsorption Syndromes / etiology
  • Male
  • Malnutrition / diagnosis
  • Malnutrition / diet therapy
  • Malnutrition / epidemiology
  • Malnutrition / etiology*
  • Middle Aged


  • Glutens