Abstract
Methanol extracts were prepared from different parts of 18 plants collected in the Yucatan peninsula and evaluated in an in vitro bioassay for leishmanicidal activity against Leishmania mexicana promastigotes. The ten most potent plant extracts (IC(50)<50 microg/ml) were Aphelandra scabra leaves, Byrsonima bucidaefolia bark, Byrsonima crassifolia bark, Clusia flava leaves, Cupania dentata bark, Diphysa carthagenensis leaves, Dorstenia contrajerva whole plant, Milleria quinqueflora roots, Tridax procumbens whole plant, and Vitex gaumeri bark.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antiprotozoal Agents / administration & dosage
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Antiprotozoal Agents / pharmacology*
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Antiprotozoal Agents / therapeutic use
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Inhibitory Concentration 50
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Leishmania mexicana / drug effects*
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Leishmaniasis, Cutaneous / drug therapy
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Medicine, Traditional
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Mexico
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Parasitic Sensitivity Tests
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Phytotherapy*
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Plant Bark
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Leaves
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Plants, Medicinal*
Substances
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Antiprotozoal Agents
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Plant Extracts