Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad-spectrum antibiotic activity

Angew Chem Int Ed Engl. 2007;46(25):4684-8. doi: 10.1002/anie.200701058.
No abstract available

MeSH terms

  • 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / antagonists & inhibitors*
  • 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / metabolism
  • Aminophenols / chemistry*
  • Aminophenols / isolation & purification*
  • Aminophenols / pharmacology
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Enzyme Inhibitors / pharmacology*
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Polycyclic Compounds / chemistry*
  • Polycyclic Compounds / isolation & purification*
  • Polycyclic Compounds / pharmacology
  • Staphylococcus aureus / enzymology

Substances

  • Aminophenols
  • Anti-Bacterial Agents
  • Enzyme Inhibitors
  • Polycyclic Compounds
  • 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase
  • platencin