This literature review explores the current evidence related to use of the Internet by hospice patients or families and palliative care/hospice professionals. The research questions guiding this study pertain to the current Internet-based interventions in hospice and palliative care and the evidence of their effectiveness. Six studies were identified as a result of an extensive literature review. These studies included research about web-based clinical interventions for patients, and patients', caregivers' and hospice/palliative care providers' use of the Internet. The majority of interventions involve accessing information via the Internet. Participants among the studies included patients, caregivers/family members, and health care professionals. Findings overall indicate effectiveness of Internet-based interventions. Both patients and professionals are using the Internet to find answers to healthcare questions, communicate, and/or deliver healthcare interventions.