The article covers data on high efficiency of differentiated program for rehabilitation of workers at high risk for dust diseases. Undertaken therapeutic course enabled to stop pneumosclerosis, better ventilation and hemodynamics, immune state, increase tolerance of physical exertion. Additional diadynamic or sinusoidal modulated currents and electrophoresis resulted in increased therapeutic efficiency. Inhalation M- cholinergic antagonists increased efficiency of medical rehabilitation and could be recommended as a part of rehabilitation programs for workers at high risk of occupational respiratory diseases.