The DEAD-box p68/p72 proteins and the noncoding RNA steroid receptor activator SRA: eclectic regulators of disparate biological functions

Cell Cycle. 2007 May 15;6(10):1172-6. doi: 10.4161/cc.6.10.4228. Epub 2007 May 3.


p68 and p72 are RNA-binding proteins endowed with RNA helicase and RNA-protein complex remodeling activities. One of the RNAs associated with p68/p72 is the noncoding Steroid Receptors RNA Activator (SRA). Here we review recent findings on the cellular processes regulated by either p68/p72 alone or in combination with SRA and discuss the transcriptional events influenced by these molecules.

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Cell Cycle / physiology*
  • DEAD-box RNA Helicases / metabolism*
  • Gene Expression Regulation*
  • Models, Biological
  • RNA, Long Noncoding
  • RNA, Untranslated / metabolism*
  • Regulatory Elements, Transcriptional / physiology*


  • RNA, Long Noncoding
  • RNA, Untranslated
  • steroid receptor RNA activator
  • DDX17 protein, human
  • DEAD-box RNA Helicases