[Arteriosclerotic plaque rupture. Its significance for myocardial infarct, sudden heart death and unstable angina]

Versicherungsmedizin. 1991 Oct 1;43(5):151-4.
[Article in German]


In coronary heart disease ruptures of atherosclerotic plaques have a key position. As a rule plaque fissuring develops in the fibrous cap of a complex atherosclerotic plaque with necrotic core. In myocardial infarction in nearly all cases mural or occlusive thrombi develop as a consequence of plaque ruptures. In instable angina, too, plaques with ruptured surfaces are very numerous but often thrombi are smaller than in patients dying from myocardial infarction. Also in cases of sudden death plaque fissurings are frequently observed. Dynamic thrombi covering plaque ruptures may be sources of microemboli in the myocardium.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Angina, Unstable / pathology*
  • Coronary Thrombosis / pathology*
  • Coronary Vessels / pathology
  • Death, Sudden, Cardiac / pathology*
  • Humans
  • Myocardial Infarction / pathology*