Tilescope: online analysis pipeline for high-density tiling microarray data

Genome Biol. 2007;8(5):R81. doi: 10.1186/gb-2007-8-5-r81.


We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data http://tilescope.gersteinlab.org. In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Computer Graphics
  • Data Interpretation, Statistical*
  • Gene Expression Profiling / standards
  • Gene Expression Profiling / statistics & numerical data
  • Models, Statistical
  • Oligonucleotide Array Sequence Analysis / standards*
  • Oligonucleotide Array Sequence Analysis / statistics & numerical data
  • Reference Standards
  • Software*