"Wunder" F-BAR Domains: Going From Pits to Vesicles

Cell. 2007 May 18;129(4):655-7. doi: 10.1016/j.cell.2007.05.006.

Abstract

Clathrin-mediated endocytosis is a key mechanism by which cells take up extracellular cargo. In this issue, Shimada et al. (2007) reveal the mode of action of the F-BAR domain, which deepens the initial membrane pit that forms during clathrin-mediated endocytosis.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Clathrin / chemistry
  • Clathrin / metabolism*
  • Clathrin-Coated Vesicles / metabolism*
  • Clathrin-Coated Vesicles / ultrastructure
  • Coated Pits, Cell-Membrane / metabolism*
  • Coated Pits, Cell-Membrane / ultrastructure
  • Endocytosis / physiology*
  • Humans
  • Ligands
  • Membrane Proteins / metabolism
  • Models, Molecular
  • Protein Structure, Tertiary / physiology
  • Receptors, Cell Surface / metabolism
  • Receptors, Cell Surface / ultrastructure

Substances

  • Clathrin
  • Ligands
  • Membrane Proteins
  • Receptors, Cell Surface