Late prosthetic joint infection due to Rothia mucilaginosa

Acta Orthop Belg. 2007 Apr;73(2):263-7.


We report a chronic hip arthroplasty infection with Rothia mucilaginosa, a Gram-positive germ belonging to the normal flora of the human oral cavity. Successful treatment was achieved by a two-stage hip arthroplasty revision and intravenous administration of vancomycin. This case report illustrates the potential virulence of R. mucilaginosa in patients with a joint prosthesis. We propose to routinely perform specific staining and prolonged culturing techniques for unusual germs such as Rothia mucilaginosa when the clinical history, physical examination or intra-operative findings suggest an implant infection. This paper reviews current antibiotic prophylaxis guidelines for infection prevention of joint arthroplasties during dental procedures.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Antibiotic Prophylaxis
  • Arthroplasty, Replacement, Hip / methods*
  • Chronic Disease
  • Comorbidity
  • Debridement
  • Diabetes Mellitus, Type 2 / epidemiology
  • Gram-Positive Bacteria / drug effects
  • Gram-Positive Bacterial Infections / epidemiology
  • Gram-Positive Bacterial Infections / surgery*
  • Hip Prosthesis / adverse effects*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Prosthesis-Related Infections / epidemiology
  • Prosthesis-Related Infections / microbiology*
  • Prosthesis-Related Infections / prevention & control
  • Prosthesis-Related Infections / surgery*
  • Reoperation
  • Risk Assessment
  • Time Factors
  • Tooth Extraction
  • Vancomycin / administration & dosage*


  • Anti-Bacterial Agents
  • Vancomycin