Acute myopericarditis after multiple vaccinations in an adolescent: case report and review of the literature

Pediatrics. 2007 Jun;119(6):e1400-3. doi: 10.1542/peds.2006-2605. Epub 2007 May 21.


We report a case of postvaccination acute myopericarditis in an adolescent. The patient presented with acute chest pain, diffuse ST-segment elevation, and elevated cardiac enzyme levels. Cardiac MRI was consistent with acute myocarditis. He recovered within a few days with nonsteroidal antiinflammatory treatment and remains clinically stable, with improvement of MRI findings at the 10-week follow-up. Postvaccination cases of myopericarditis reported in the pediatric literature are also reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acute Disease
  • Adolescent
  • Diphtheria-Tetanus-acellular Pertussis Vaccines / adverse effects
  • Hepatitis A Vaccines / adverse effects
  • Humans
  • Male
  • Meningococcal Vaccines / adverse effects
  • Myocarditis / diagnosis*
  • Myocarditis / etiology
  • Myocarditis / physiopathology
  • Pericarditis / diagnosis*
  • Pericarditis / etiology
  • Pericarditis / physiopathology
  • Vaccination / adverse effects*


  • Diphtheria-Tetanus-acellular Pertussis Vaccines
  • Hepatitis A Vaccines
  • Meningococcal Vaccines