Radioembolization with 90Y microspheres: angiographic and technical considerations

Cardiovasc Intervent Radiol. 2007 Jul-Aug;30(4):571-92. doi: 10.1007/s00270-007-9064-z. Epub 2007 May 22.


The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

Publication types

  • Review

MeSH terms

  • Angiography / methods*
  • Brachytherapy / methods*
  • Carcinoma, Hepatocellular / blood supply
  • Carcinoma, Hepatocellular / diagnostic imaging
  • Carcinoma, Hepatocellular / radiotherapy*
  • Catheterization, Peripheral / methods
  • Celiac Artery / abnormalities
  • Celiac Artery / diagnostic imaging
  • Embolization, Therapeutic / methods*
  • Hepatic Artery / abnormalities
  • Hepatic Artery / diagnostic imaging*
  • Humans
  • Infusions, Intra-Arterial / methods
  • Liver / blood supply
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / radiotherapy*
  • Magnetic Resonance Angiography
  • Mesenteric Arteries / abnormalities
  • Mesenteric Arteries / diagnostic imaging
  • Microspheres
  • Neovascularization, Pathologic / diagnostic imaging
  • Neovascularization, Pathologic / radiotherapy
  • Regional Blood Flow / physiology
  • Stomach / blood supply
  • Tomography, X-Ray Computed
  • Yttrium Radioisotopes / therapeutic use*


  • Yttrium Radioisotopes