Papillary thyroid carcinoma in a patient with sarcoidosis treated with minocycline

N A Bruins; J E Oswald; H Morreau; J Kievit; S Pavel; A H M Smelt

Papillary thyroid carcinoma in a patient with sarcoidosis treated with minocycline

Neth J Med. 2007 May;65(5):185-7.

Authors

N A Bruins¹, J E Oswald, H Morreau, J Kievit, S Pavel, A H M Smelt

Affiliation

¹ Department of General Internal Medicine and Endocrinology, Leiden University Medical Centre, Leiden, the Netherlands.

PMID: 17519514

Abstract

Long-term treatment with minocycline is occasionally associated with the development of black thyroid syndrome in which thyroid cancer is frequently found. Here, we report a patient with cutaneous, pulmonary and thyroid sarcoidosis who developed papillary thyroid carcinoma in the presence of a black thyroid syndrome after being treated with minocycline for 2.5 years.

Publication types

Case Reports

MeSH terms

Adult
Anti-Bacterial Agents / adverse effects*
Carcinoma, Papillary / chemically induced*
Carcinoma, Papillary / pathology
Carcinoma, Papillary / surgery
Female
Humans
Minocycline / adverse effects*
Pigmentation / drug effects
Sarcoidosis / drug therapy*
Thyroid Neoplasms / chemically induced*
Thyroid Neoplasms / pathology
Thyroid Neoplasms / surgery
Thyroidectomy

Substances

Anti-Bacterial Agents
Minocycline