Evaluating dosage compensation as a cause of duplicate gene retention in Paramecium tetraurelia

Genome Biol. 2007;8(5):213. doi: 10.1186/gb-2007-8-5-213.


The high retention of duplicate genes in the genome of Paramecium tetraurelia has led to the hypothesis that most of the retained genes have persisted because of constraints due to gene dosage. This and other possible mechanisms are discussed in the light of expectations from population genetics and systems biology.

Publication types

  • Review

MeSH terms

  • Animals
  • Dosage Compensation, Genetic*
  • Gene Duplication*
  • Genetics, Population
  • Genome, Protozoan
  • Paramecium tetraurelia / genetics*
  • Systems Biology