Human-hemato-lymphoid-system mice: opportunities and challenges

Immunity. 2007 May;26(5):537-41. doi: 10.1016/j.immuni.2007.05.001.


With the recent advances in human-hemato-lymphoid-system mice, this commentary discusses the utility of these mice and further improvements required to generate an accessible system that allows predictive in vivo human hematology and immunology research.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation
  • Cross Reactions / immunology
  • Hematopoietic System / cytology
  • Hematopoietic System / immunology*
  • Humans
  • Lymphocytes / cytology
  • Lymphocytes / immunology*
  • Mice