Corneal perforation associated with pellucid marginal degeneration and treatment with crescentic lamellar keratoplasty: two case reports

Cornea. 2007 Jun;26(5):625-8. doi: 10.1097/ICO.0b013e3180398e93.


Purpose: To describe 2 cases of corneal perforation associated with pellucid marginal degeneration (PMD) and subsequent successful management with crescentic lamellar keratoplasty.

Methods: Two cases are discussed along with the relevant literature.

Results: Both patients presented with spontaneous corneal perforations and associated features consistent with PMD. In both cases, there was fellow eye evidence of PMD, and 1 of the patients was already known to our unit with this diagnosis. Initial conservative measures were unsuccessful, and both patients underwent crescentic lamellar keratoplasty as the definitive surgical management with a good visual outcome.

Conclusions: Crescentic lamellar keratoplasty is an effective technique for the management of this rare complication of PMD.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cornea / pathology
  • Cornea / surgery*
  • Corneal Diseases / diagnosis
  • Corneal Diseases / etiology
  • Corneal Diseases / surgery
  • Corneal Dystrophies, Hereditary / complications*
  • Corneal Dystrophies, Hereditary / diagnosis
  • Corneal Dystrophies, Hereditary / surgery*
  • Corneal Topography
  • Corneal Transplantation*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Rupture, Spontaneous
  • Visual Acuity