A clear correlation was found between the development of stenosing laryngotracheitis (SLT) in the presence of viral infection, its severity, and the environment well-being of an area where a child resides. The level of environmental pollution and the interaction of environmental factors and weather-climatic ill-being, which vary with time and have regional features, adversely affect the course of SLT and require mandatory correction during complex therapy and seasonal antirecurrent treatment. The increase in the incidence of childhood SLT may be a biological indicator of the environmental ill-being of a region.