Thermoregulation of Escherichia coli hchA transcript stability

J Bacteriol. 2007 Aug;189(15):5779-81. doi: 10.1128/JB.00453-07. Epub 2007 May 25.


The conserved chaperone Hsp31 of Escherichia coli is transcribed at low temperatures by sigma(S) and repressed by H-NS, whereas at high temperature, transcription is by sigma70 independently of both sigma(S) and H-NS. Here we present evidence for an additional, novel, temperature-dependent control of Hsp31 expression by increased transcript stability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Escherichia coli / physiology*
  • Escherichia coli Proteins / biosynthesis*
  • Gene Expression Regulation, Bacterial / physiology*
  • Molecular Chaperones / biosynthesis*
  • RNA Stability*
  • RNA, Bacterial / metabolism
  • RNA, Messenger / metabolism*
  • Temperature*


  • Escherichia coli Proteins
  • Molecular Chaperones
  • RNA, Bacterial
  • RNA, Messenger
  • hchA protein, E coli