Coronavirus envelope protein: a small membrane protein with multiple functions

Cell Mol Life Sci. 2007 Aug;64(16):2043-8. doi: 10.1007/s00018-007-7103-1.


Coronavirus envelope protein is a small membrane protein and minor component of the virus particles. It plays important roles in virion assembly and morphogenesis, alteration of the membrane permeability of host cells and virus-host cell interaction. Here we review recent progress in characterization of the biochemical properties, membrane topology and functions of the protein.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Apoptosis
  • Coronavirus / metabolism*
  • Ion Channels / metabolism
  • Molecular Sequence Data
  • Sequence Alignment
  • Viral Envelope Proteins / genetics
  • Viral Envelope Proteins / metabolism*
  • Virion / metabolism


  • Ion Channels
  • Viral Envelope Proteins