Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria

Eur J Clin Invest. 2007 Jun;37(6):435-53. doi: 10.1111/j.1365-2362.2007.01807.x.


Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and treatment responses. To address these demands, leading experts discussed current issues and standards in mastocytosis in a Working Conference. The present article provides the resulting outcome with consensus statements, which focus on the appropriate application of clinical and laboratory tests, patient selection for interventional therapy, and the selection of appropriate drugs. In addition, treatment response criteria for the various clinical conditions, disease-specific symptoms, and specific pathologies are provided. Resulting recommendations and algorithms should greatly facilitate the management of patients with mastocytosis in clinical practice, selection of patients for therapies, and the conduct of clinical trials.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic / methods
  • Clinical Trials as Topic / standards
  • Diagnosis, Differential
  • Humans
  • Mastocytosis / diagnosis*
  • Mastocytosis / therapy
  • Patient Selection