Abstract
In 38 African AIDS patients initiating generic HAART, GB virus C (GBV-C) RNA-positive patients retained GBV-C viraemia during 52 weeks of HAART, had a faster decline in HIV viral load (P = 0.03), fewer opportunistic infections (14.3 versus 50%, P = 0.18), and suffered no serious adverse events (none versus 61%, P = 0.008) compared with patients without GBV-C. GBV-C co-infection may be associated with a beneficial effect on African AIDS patients treated with generic HAART.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / epidemiology
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Acquired Immunodeficiency Syndrome / complications
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Acquired Immunodeficiency Syndrome / epidemiology
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Adult
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Africa / epidemiology
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Antiretroviral Therapy, Highly Active / methods*
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Female
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Flaviviridae Infections / complications
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Flaviviridae Infections / epidemiology*
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GB virus C*
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HIV Infections / complications
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HIV Infections / drug therapy*
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HIV Infections / epidemiology
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HIV-1*
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Hepatitis, Viral, Human / complications
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Hepatitis, Viral, Human / epidemiology*
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Herpesviridae Infections / complications
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Herpesviridae Infections / epidemiology
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Humans
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Male
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Middle Aged
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Prevalence
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RNA, Viral / analysis
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Retrospective Studies
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Sarcoma, Kaposi / complications
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Sarcoma, Kaposi / epidemiology
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Viremia / complications
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Viremia / epidemiology