Long-term outcomes in patients requiring stay of more than 48 hours in the intensive care unit following coronary bypass surgery

J Crit Care. 2007 Jun;22(2):153-8. doi: 10.1016/j.jcrc.2006.09.009. Epub 2007 Jan 31.

Abstract

Background: The primary objective of this study was to determine the long-term outcomes of all patients requiring prolonged intensive care unit (ICU) stay following coronary bypass surgery (CABG) surgery.

Methods: All patients undergoing CABG surgery between 1998 and 2002 were reviewed. Prolonged ICU stay was defined as more than 48 hours. Short-term (in-hospital) and long-term (postdischarge) outcomes were evaluated using available databases.

Results: Of 3139 patients who underwent CABG surgery, 598 required an ICU stay of more than 48 hours (19%). The in-hospital mortality for patients requiring prolonged ICU stay was 10.0% as compared with 1.2% for the remainder of patients (P < .0001). The median length of hospitalization for patients requiring prolonged stay was 11 days (IQR 7-18) as compared to 6 days (IQR 5-7). The median follow-up of patients who survived to discharge was 31 months with a 100% follow-up. Using Cox proportional hazard ratio, patients who required a prolonged ICU stay were found to have a significant lower survival and freedom from cardiac readmission to the hospital. Prolonged ICU stay was an independent predictor of composite outcome (death + readmission) with a hazard ratio of 1.8 (1.5-2.1).

Conclusions: Prolonged ICU stay following CABG resulted in increased early and late mortality and lower freedom from readmission to hospital for cardiac reasons.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Coronary Artery Bypass* / mortality
  • Female
  • Hospital Mortality
  • Humans
  • Intensive Care Units / statistics & numerical data*
  • Kaplan-Meier Estimate
  • Length of Stay*
  • Male
  • Middle Aged
  • Nova Scotia / epidemiology
  • Patient Readmission / statistics & numerical data
  • Postoperative Period
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome