Lyme disease associated with postganglionic Horner syndrome and Raeder paratrigeminal neuralgia

J Neuroophthalmol. 2007 Jun;27(2):123-4. doi: 10.1097/WNO.0b013e318064e4ba.


A 55-year-old woman developed severe unilateral headaches, periocular numbness, and Horner syndrome after presenting with symptoms consistent with Lyme disease. The combination of Horner syndrome and periocular headache and numbness constituted a diagnosis of Raeder paratrigeminal neuralgia. Although the headaches resolved with antibiotic treatment, the Horner syndrome persisted for at least 1 year. This case expands the spectrum of neurologic manifestations of Lyme disease to include postganglionic Horner syndrome as well as Raeder paratrigeminal neuralgia.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Horner Syndrome / complications*
  • Humans
  • Lyme Disease / complications*
  • Middle Aged
  • Trigeminal Neuralgia / complications*