Acute febrile neutrophilic dermatosis (Sweet's syndrome): a study of 15 cases in Iran

Int J Dermatol. 2007 Jun;46(6):571-4. doi: 10.1111/j.1365-4632.2005.02688.x.


Background: Sweet's syndrome is well recognized by dermatologists and is not infrequently diagnosed in Iran; however, few case series have been reported.

Methods: A clinicopathologic study was carried out on 15 cases of Sweet's syndrome in Hamedan, in the west of Iran, between 1994 and 2004.

Results: The incidence of Sweet's syndrome was 3 per 10,000 amongst new dermatologic patients. All were women with a mean age of 58 years. All 15 cases were of the classic type, with no associated diseases. Fever was seen in only six (40%) patients.

Conclusions: Sweet's syndrome has a broad spectrum of clinical and pathologic findings in various areas of the world. Further investigation is necessary to determine the etiology and effect of environmental factors in this disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Incidence
  • Iran / epidemiology
  • Middle Aged
  • Prednisolone / therapeutic use
  • Retrospective Studies
  • Skin / pathology
  • Sweet Syndrome / diagnosis
  • Sweet Syndrome / epidemiology*
  • Sweet Syndrome / therapy


  • Prednisolone