doi: 10.1016/j.tig.2007.05.007.
Epub 2007 Jun 6.
Comparative genomics reveals novel biochemical pathways
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- PMID: 17555842
- DOI: 10.1016/j.tig.2007.05.007
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Comparative genomics reveals novel biochemical pathways
Trends Genet.
2007 Aug.
Abstract
How well do we understand which enzymes are involved in the primary metabolism of the cell? A recent study using comparative genomics and postgenomics approaches revealed a novel pathway in the most studied organism, Escherichia coli. The analysis of a new operon consisting of seven previously uncharacterized genes thought to be involved in the degradation of nucleic acid precursors shows the impact of comparative genomics on the discovery of novel pathways and enzymes.
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