Inherited renal acidoses

Physiology (Bethesda). 2007 Jun;22:202-11. doi: 10.1152/physiol.00044.2006.


Inherited acidosis may result from a primary renal defect in acid-base handling, emphasizing the central role of the kidney in control of body pH; as a secondary phenomenon resulting from abnormal renal electrolyte handling; or from excess production of acid elsewhere in the body. Here, we review our current understanding of the inherited renal acidoses at a genetic and molecular level.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acid-Base Imbalance / genetics*
  • Acid-Base Imbalance / metabolism*
  • Acidosis, Renal Tubular / genetics*
  • Acidosis, Renal Tubular / metabolism*
  • Animals
  • Humans
  • Kidney Tubules / metabolism*