The role of complement in inflammation and phagocytosis

Immunol Today. 1991 Sep;12(9):322-6. doi: 10.1016/0167-5699(91)90009-I.


Inflammation and phagocytosis are highly complex events involving many humoral and cellular factors, with complement components playing a key role. As described here by Mike Frank and Louis Fries, complement peptides trigger cell function, aid in the recognition of invading pathogens and regulate the phagocytic process via interactions with specific cell surface receptors.

Publication types

  • Review

MeSH terms

  • Complement System Proteins / immunology*
  • Humans
  • Inflammation*
  • Phagocytosis / immunology*


  • Complement System Proteins