Maturation and degradation of RNA in bacteria

Curr Opin Microbiol. 2007 Jun;10(3):271-8. doi: 10.1016/j.mib.2007.05.008. Epub 2007 Jun 7.


RNA decay plays an important role, not only in recycling nucleotides but also in determining the rapidity with which cells can react to changing growth conditions. The degradation process can be regulated, thus providing an often-underestimated means of controlling gene expression. Recent developments in the field of RNA maturation and decay in two key model organisms, Escherichia coli and Bacillus subtilis, include the resolution of the structures of many of the participants in these processes in E. coli and the identification of an enzyme in B. subtilis that appears to fit the bill as a major player in RNA decay in this organism.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacillus subtilis / genetics
  • Bacillus subtilis / metabolism
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Models, Biological
  • Nucleic Acid Conformation
  • RNA Processing, Post-Transcriptional*
  • RNA Stability
  • RNA, Bacterial / chemistry
  • RNA, Bacterial / genetics
  • RNA, Bacterial / metabolism*


  • RNA, Bacterial