Indications for flexible fiberoptic bronchoscopy and its safety in the very elderly

Monaldi Arch Chest Dis. 2007 Mar;67(1):23-9. doi: 10.4081/monaldi.2007.506.


Aim: To evaluate the indications and the safety of fiberoptic bronchoscopy (FOB) with bronchoalveolar lavage (BAL), protected specimen brushing (PSB), endobronchial biopsy (EBB), and transbronchial biopsy (TBB) in a population of very elderly patients.

Methods: We performed a retrospective study of all adult patients, aged 50 years or older, who underwent FOB in the Bronchology Unit of the University of Parma Hospital between 1 January, 2003 and 31 April, 2005. Bronchoscopy records of 436 consecutive patients, including 191 patients, 75 yrs of age and older ("very elderly"; = > 75 yrs), were reviewed.

Results: Patients aged < 75 years and aged =/> 75 years were no different with regard to gender, BMI, baseline FEV1/FVC ratio, baseline SaO2, and blood pressure. The primary indication in patients aged < 75 years, was to assist in the diagnosis of a pulmonary mass of unknown aetiology (33%) and to remove secretions in the very elderly patients (31%). Indications for FOB and sampling procedures in the two groups were similar. Approximately 30% of patients in each group required supplemental oxygen during the procedure and fever occurred in 9.2% and 10.3% of patients, respectively. Hypertension and bleeding were relatively rare and did not occur more often in the very elderly.

Conclusions: Indication for FOB did not vary with age and adverse events in both groups were uncommon and generally not severe.

Publication types

  • Evaluation Study

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Bronchi / pathology
  • Bronchoalveolar Lavage Fluid
  • Bronchoscopy* / adverse effects
  • Equipment Safety
  • Female
  • Fiber Optic Technology*
  • Forced Expiratory Volume
  • Humans
  • Italy
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / physiopathology
  • Male
  • Middle Aged
  • Research Design
  • Retrospective Studies
  • Specimen Handling