Streptococcus pneumoniae-associated hemolytic uremic syndrome

Pediatr Nephrol. 2008 Nov;23(11):1951-6. doi: 10.1007/s00467-007-0518-y. Epub 2007 Jun 13.


Streptococcus pneumonia-associated hemolytic uremic syndrome (HUS) (pneumococcal HUS) is an uncommon condition mainly observed in young children. Early recognition is critical, because of the potential to improve morbidity and mortality. In our review we summarize the pathophysiology, clinical features, diagnostic difficulties and management of this potentially under-diagnosed condition.

Publication types

  • Review

MeSH terms

  • Child
  • Education, Medical, Continuing
  • Hemolytic-Uremic Syndrome / microbiology*
  • Hemolytic-Uremic Syndrome / pathology*
  • Hemolytic-Uremic Syndrome / therapy
  • Humans
  • Pneumococcal Infections / complications*
  • Pneumococcal Infections / pathology*
  • Pneumococcal Infections / therapy
  • Streptococcus pneumoniae*