Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor

Angew Chem Int Ed Engl. 2007;46(28):5352-5. doi: 10.1002/anie.200700762.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemical synthesis
  • Amides / chemistry*
  • Carboxylic Acids / chemistry*
  • DNA / chemistry
  • DNA / metabolism
  • Homeodomain Proteins / chemistry
  • Homeodomain Proteins / metabolism
  • Lactams / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Stereoisomerism
  • Transcription Factors / antagonists & inhibitors*
  • Transcription Factors / metabolism

Substances

  • Amides
  • Carboxylic Acids
  • Homeodomain Proteins
  • Lactams
  • Transcription Factors
  • homeobox protein HOXA13
  • DNA