Pneumococcal vaccination in adults: recommendations, trends, and prospects

Cleve Clin J Med. 2007 Jun;74(6):401-6, 408-10, 413-4. doi: 10.3949/ccjm.74.6.401.


The US Centers for Disease Control and Prevention recommends vaccination against Streptococcus pneumoniae for all people age 65 and older and also for younger people at high risk. However, experts continue to debate the efficacy of the vaccine; most observational studies found it beneficial, while clinical trials were inconclusive as a group. Although pneumococcal vaccination may or may not protect against pneumonia or death from any cause, it does significantly decrease the risk of invasive pneumococcal disease and is worthwhile for this reason.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Age Factors
  • Centers for Disease Control and Prevention, U.S.
  • Humans
  • Pneumococcal Infections / microbiology
  • Pneumococcal Infections / prevention & control*
  • Pneumococcal Vaccines / administration & dosage
  • Pneumococcal Vaccines / immunology
  • Pneumococcal Vaccines / supply & distribution*
  • Practice Guidelines as Topic*
  • Risk Assessment
  • Risk Factors
  • Streptococcal Infections / prevention & control*
  • United States
  • Vaccination / standards*
  • Vaccination / statistics & numerical data


  • Pneumococcal Vaccines