Gastric inflammatory fibroid polyp treated with Helicobacter pylori eradication therapy

Intern Med. 2007;46(12):855-8. doi: 10.2169/internalmedicine.46.6445. Epub 2007 Jun 15.


Gastric inflammatory fibroid polyps (IFPs) are rare benign lesions that occur in the distal stomach. We describe a 56-year-old woman with Helicobacter pylori (H. pylori)-positive gastric IFP treated with eradication. Endoscopic examination revealed a submucosal tumor, 35 mm in diameter, with an ulcerated apex at the antrum. H. pylori were positive by both histology and tissue culture, and eradication (a proton pump inhibitor, amoxicillin, and clarithromycin) was performed. After 6 months, the tumor morphologically changed and decreased in size. This case suggests that H. pylori may play a role in the pathogenesis of gastric IFPs.

Publication types

  • Case Reports

MeSH terms

  • Amoxicillin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Gastric Mucosa / microbiology
  • Helicobacter Infections / complications*
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / drug therapy*
  • Helicobacter pylori / isolation & purification*
  • Humans
  • Middle Aged
  • Polyps / diagnosis
  • Polyps / drug therapy*
  • Polyps / microbiology*
  • Proton Pump Inhibitors
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / microbiology*
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Proton Pump Inhibitors
  • Amoxicillin
  • Clarithromycin