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Review
. 2007 Sep;75(9):4199-210.
doi: 10.1128/IAI.01927-06. Epub 2007 Jun 18.

Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation

Jay L Mellies  1 , Alex M S Barron, Anna M Carmona
Affiliations
Review

Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation

Jay L Mellies et al. Infect Immun. 2007 Sep.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Regulation of the LEE PAI in EPEC (A) and EHEC (B). Thin arrows represent positive regulatory signals, and thin blunt arrows represent negative signals. Solid arrows indicate expression of regulatory proteins. Horizontally acquired regulatory proteins appear in ovals with a black background, and regulatory proteins endogenous to E. coli are within ovals with a white background. See Tables 1 and 2 for listings of specific regulators.
FIG. 2.
FIG. 2.
Virulence gene regulation in the EAF plasmid of EPEC (A) and the EHEC pO157 plasmid (B). Thin arrows represent positive regulatory signals, and thin blunt arrows represent negative signals. Solid arrows indicate expression of regulatory proteins. Horizontally acquired regulatory proteins appear in ovals with a black background. Regulation of bfp in response to NH4+ concentrations in EPEC is noted by box. The EtrA and EivF proteins of EHEC are encoded in a second cryptic TTSS, termed ETT2, of the Sakai 813 strain.
FIG. 3.
FIG. 3.
Quorum-sensing signaling of flagellar motility and AE lesion formation in EPEC and EHEC. The cryptic phage-encoded TccP protein is necessary for AE lesion formation in EHEC. See the text for details.
See this image and copyright information in PMC

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References

    1. Aertsen, A., R. Van Houdt, and C. W. Michiels. 2005. Construction and use of an stx1 transcriptional fusion to gfp. FEMS Microbiol. Lett. 245:73-77. - PubMed
    1. Aldea, M., T. Garrido, J. Pla, and M. Vicente. 1990. Division genes in Escherichia coli are expressed coordinately to cell septum requirements by gearbox promoters. EMBO J. 9:3787-3794. - PMC - PubMed
    1. Barba, J., V. H. Bustamante, M. A. Flores-Valdez, W. Deng, B. B. Finlay, and J. L. Puente. 2005. A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA. J. Bacteriol. 187:7918-7930. - PMC - PubMed
    1. Beltrametti, F., A. U. Kresse, and C. A. Guzmâan. 1999. Transcriptional regulation of the esp genes of enterohemorrhagic Escherichia coli. J. Bacteriol. 181:3409-3418. - PMC - PubMed
    1. Berdichevsky, T., D. Friedberg, C. Nadler, A. Rokney, A. Oppenheim, and I. Rosenshine. 2005. Ler is a negative autoregulator of the LEE1 operon in enteropathogenic Escherichia coli. J. Bacteriol. 187:349-357. - PMC - PubMed

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