Abstract
The synthesis of new indole alkaloid analogues, containing a 1,2,4,5,10b,10c-hexahydropyrrolo[1',2',3':1,9a,9]imidazo[1,2-a]indole skeleton, via highly stereoselective novel domino cyclative halogenation or prenylation reactions of tryptophan-derived alpha-amino nitriles, is described.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amination
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Bromine / chemistry
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Chlorine / chemistry
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Cyclization
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Electrons
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Imidazoles / chemistry
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Indole Alkaloids / chemical synthesis
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Indole Alkaloids / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Nitriles / chemistry*
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Stereoisomerism
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Tryptophan / chemistry*
Substances
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Imidazoles
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Indole Alkaloids
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Nitriles
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Chlorine
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Tryptophan
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Bromine