Surface modification of resorcinarene based self-assembled solid lipid nanoparticles for drug targeting

Chem Commun (Camb). 2007 Jul 7:(25):2605-7. doi: 10.1039/b703106h. Epub 2007 Apr 13.

Abstract

Prolyl-bearing amphiphilic resorcinarenes, e.g. tetrakis(N-methylprolyl)tetraundecylcalix[4]resorcinarene, self-assemble as stable solid lipid nanoparticles; these fully characterized systems could be further functionalized at their surface with proteins, and interact with specific antibodies bound on a sensor surface.

MeSH terms

  • Calixarenes / chemistry*
  • Drug Delivery Systems
  • Microscopy, Atomic Force
  • Microscopy, Electron, Scanning
  • Nanoparticles / chemistry*
  • Particle Size
  • Phenylalanine / analogs & derivatives*
  • Phenylalanine / chemistry
  • Serum Albumin, Bovine / chemistry

Substances

  • resorcinarene
  • Calixarenes
  • Serum Albumin, Bovine
  • Phenylalanine