A Genome Scan for Quantitative Trait Locus by Environment Interactions for Production Traits

J Dairy Sci. 2007 Jul;90(7):3482-9. doi: 10.3168/jds.2006-834.

Abstract

Genotype by environment interactions between milk production traits and production level have often been observed. To increase the power of quantitative trait loci (QTL) detection, QTL by environment interaction was included in QTL analyses for the milk, protein, and fat yields. The aim of the study was to detect QTL with interaction effects with the production environment. The QTL effects were modeled through random regression models for within-herd production level. All autosomes except Bos taurus autosome 6 were included in the analysis. A more detailed study of chromosome 6 is planned. For milk yield, 5 QTL were observed, 2 of which had interaction effects with production level (suggestive linkage). For protein yield, 5 QTL were observed, 3 of which had interaction effects (suggestive linkage). For fat yield, 3 QTL were observed, none of which had interaction effects with the environment (suggestive linkage). Thus, some QTL with interaction effects seemingly exist for milk yield and protein yield. For such QTL, estimated correlations between slope and intercept of the effect (close to 1 or -1) indicated that only 2 alleles were segregating. The study indicates that QTL by environment interactions exist, and that random regression models that describe the environment as herd production level can detect this interaction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle / genetics*
  • Chromosome Mapping
  • Environment*
  • Female
  • Genome*
  • Haplotypes / genetics
  • Lactation / genetics*
  • Male
  • Microsatellite Repeats
  • Milk / chemistry
  • Milk / metabolism
  • Milk Proteins / analysis
  • Models, Genetic
  • Models, Statistical
  • Phenotype
  • Quantitative Trait Loci / genetics*
  • Regression Analysis

Substances

  • Milk Proteins