Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage

J Clin Neurosci. 2007 Sep;14(9):890-5. doi: 10.1016/j.jocn.2006.06.011. Epub 2007 Jun 19.


Cerebral sinus thrombosis is a rare cause of spontaneous subarachnoid hemorrhage. The development of cerebral sinus thrombosis as a complication of heparin-induced thrombocytopenia is even rarer. In this paper, we present a 59-year-old patient admitted to our service with cerebral sinus thrombosis secondary to type II heparin-induced thrombocytopenia. We also review the literature in regard to the incidence, pathophysiology and management of this rare clinicopathological entity.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology
  • Female
  • Heparin / adverse effects*
  • Humans
  • Kidney Failure, Chronic / therapy
  • Magnetic Resonance Imaging / methods
  • Middle Aged
  • Renal Dialysis / methods
  • Sagittal Sinus Thrombosis / diagnosis*
  • Sagittal Sinus Thrombosis / etiology*
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / complications*
  • Tomography, X-Ray Computed / methods


  • Heparin