FGF: a web tool for Fishing Gene Family in a whole genome database

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W121-5. doi: 10.1093/nar/gkm426. Epub 2007 Jun 21.


Gene duplication is an important process in evolution. The availability of genome sequences of a number of organisms has made it possible to conduct comprehensive searches for duplicated genes enabling informative studies of their evolution. We have established the FGF (Fishing Gene Family) program to efficiently search for and identify gene families. The FGF output displays the results as visual phylogenetic trees including information on gene structure, chromosome position, duplication fate and selective pressure. It is particularly useful to identify pseudogenes and detect changes in gene structure. FGF is freely available on a web server at http://fgf.genomics.org.cn/

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Animals
  • Chromosome Mapping
  • Chromosomes / ultrastructure
  • Computational Biology / methods*
  • Evolution, Molecular
  • Gene Duplication*
  • Genome*
  • Humans
  • Information Storage and Retrieval
  • Internet*
  • Models, Genetic
  • Phylogeny
  • Software
  • User-Computer Interface