Synthetic applications of cyanoacetylated bisindoles: synthesis of novel cycloheptadiindoles, indolocarbazoles, and related aza analogues

J Org Chem. 2007 Jul 20;72(15):5886-9. doi: 10.1021/jo0706729. Epub 2007 Jun 22.

Abstract

Cyclization reactions involving cyanoacetylated bisindoles have been studied, providing access to various novel cyclohepta[2,1-b:3,4-b']diindole derivatives as well as some related fused pentacyclic systems. Treatment of 3-cyanoacetyl-2,3'-diindolylmethane with methanesulfonic acid gave 6-(cyanomethyl)indolo[3,2-b]carbazole in a good yield.

MeSH terms

  • Acetylation
  • Aza Compounds / chemical synthesis*
  • Carbazoles / chemical synthesis*
  • Indoles / chemical synthesis*
  • Magnetic Resonance Spectroscopy
  • Spectrometry, Mass, Fast Atom Bombardment
  • Spectrophotometry, Infrared

Substances

  • Aza Compounds
  • Carbazoles
  • Indoles