Vacuum-assisted closure in the treatment of poststernotomy mediastinitis in the paediatric patient

J Plast Reconstr Aesthet Surg. 2008;61(3):302-5. doi: 10.1016/j.bjps.2007.05.004. Epub 2007 Jun 27.

Abstract

Introduction: Delayed sternal closure after paediatric open heart procedure is often necessary. The risk of delayed sternal closure is infection: superficial wound or sternal and mediastinal infection. The incidence of sternal wound infection reported in the literature varies from 0.5 to 10%. The mortality for poststernotomy deep sternal infection continues to be high--from 14 to 47%. Established treatment includes surgical debridement, drainage and irrigation, antibiotics, frequent change of wound dressing and direct or secondary closure with omentum or pectoral muscle flap.

Patients and methods: Between October 2003 and August 2005, three children, aged from 9 days to 2 years and who had developed severe mediastinitis after cardiac surgery were treated with the vacuum-assisted closure (VAC) system.

Results: The duration of VAC treatment ranged from 12 to 21 days. The response to VAC was rapid with local purulence and C-reactive protein (CRP) both decreasing within 72 h in all cases. After good granulation was obtained, two patients required a thin skin graft.

Discussion: All three children had peritoneal dialysis which did not permit omental use. The use of pectoralis major is a difficult technique in neonates and the haemodynamic conditions were poor in our cases. The VAC technique is a good indication in post-cardiotomy mediastinitis in children: it plays a role in the reduction of infection and provides good healing.

Publication types

  • Evaluation Study

MeSH terms

  • C-Reactive Protein / metabolism
  • Child, Preschool
  • Heart Defects, Congenital / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mediastinitis / pathology
  • Mediastinitis / therapy*
  • Necrosis
  • Patient Selection
  • Postoperative Complications / pathology
  • Postoperative Complications / therapy*
  • Sternum / surgery*
  • Surgical Wound Dehiscence / therapy
  • Surgical Wound Infection / pathology
  • Surgical Wound Infection / therapy
  • Treatment Outcome
  • Vacuum*
  • Wound Healing

Substances

  • C-Reactive Protein