Stevens-Johnson syndrome, drug-induced hypersensitivity syndrome and toxic epidermal necrolysis caused by allopurinol in patients with a common HLA allele: what causes the diversity?

Dermatology. 2007;215(1):86-8. doi: 10.1159/000102045.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alleles
  • Allopurinol / adverse effects*
  • Allopurinol / therapeutic use
  • Drug Eruptions
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / genetics
  • Drug Hypersensitivity / physiopathology
  • Follow-Up Studies
  • Gout / drug therapy
  • Gout / genetics
  • HLA-B Antigens / genetics*
  • Humans
  • Male
  • Middle Aged
  • Risk Assessment
  • Sampling Studies
  • Stevens-Johnson Syndrome / chemically induced*
  • Stevens-Johnson Syndrome / etiology*
  • Stevens-Johnson Syndrome / genetics
  • Stevens-Johnson Syndrome / physiopathology
  • Syndrome

Substances

  • HLA-B Antigens
  • Allopurinol