Abstract
Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to medication. In this report, we present two children with brain tumour who developed SJS while receiving cranial irradiation and anticonvulsant therapy with phenobarbital. Concomitant application of these two therapies may play an important role in the occurrence of the disease.
MeSH terms
-
Anticonvulsants / adverse effects*
-
Brain Neoplasms / complications*
-
Brain Neoplasms / radiotherapy
-
Brain Neoplasms / surgery
-
Child
-
Combined Modality Therapy / adverse effects
-
Cranial Irradiation / adverse effects*
-
Female
-
Humans
-
Male
-
Medulloblastoma / complications*
-
Medulloblastoma / radiotherapy
-
Medulloblastoma / surgery
-
Phenobarbital / adverse effects*
-
Stevens-Johnson Syndrome / etiology*
-
Treatment Outcome
Substances
-
Anticonvulsants
-
Phenobarbital