Diffusion-weighted imaging of the brain in infants and children

Pediatr Radiol. 2007 Aug;37(8):749-68. doi: 10.1007/s00247-007-0515-0. Epub 2007 Jun 23.


During the last decade, diffusion-weighted imaging (DWI) has become an important tool in the evaluation of a variety of disorders of the central nervous system in children. DWI relies on variability in the diffusivity of water molecules in the presence of a supplemental diffusion-sensitizing gradient to produce image contrast. Pathologic states alter the diffusion characteristics of brain water in a reproducible fashion. In this review, the DWI appearances of a number of common abnormalities of the brain in infants and children are presented.

Publication types

  • Review

MeSH terms

  • Brain / pathology*
  • Brain Diseases / diagnosis*
  • Brain Mapping / methods
  • Child
  • Child, Preschool
  • Diffusion Magnetic Resonance Imaging*
  • Humans
  • Infant
  • Infant, Newborn