Interstitial pneumonitis and alveolar hemorrhage complicating use of rituximab: case report and review of the literature

Gustavo A Heresi; Carol F Farver; James K Stoller

doi:10.1159/000104866

Interstitial pneumonitis and alveolar hemorrhage complicating use of rituximab: case report and review of the literature

Respiration. 2008;76(4):449-53. doi: 10.1159/000104866. Epub 2007 Jun 27.

Authors

Gustavo A Heresi¹, Carol F Farver, James K Stoller

Affiliation

¹ Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA.

PMID: 17596682
DOI: 10.1159/000104866

Abstract

The use of rituximab has been uncommonly associated with delayed pulmonary toxicity. We present a case of interstitial pneumonitis and diffuse alveolar hemorrhage, which represents the second such case reported in the literature.

Publication types

Case Reports
Review

MeSH terms

Aged, 80 and over
Antibodies, Monoclonal / adverse effects*
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Agents / adverse effects*
Hemoptysis / chemically induced*
Humans
Lung Diseases, Interstitial / chemically induced*
Male
Rituximab
Waldenstrom Macroglobulinemia / drug therapy

Substances

Antibodies, Monoclonal
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Agents
Rituximab