Screening of depressive symptoms in young-old hemodialysis patients: relationship between Beck Depression Inventory and 15-item Geriatric Depression Scale

Nephron Clin Pract. 2007;106(4):c187-92. doi: 10.1159/000104430. Epub 2007 Jun 26.


Aims: We studied the relationship between the Beck Depression Inventory (BDI) and the 15-item Geriatric Depression Scale (GDS-15) in young-old hemodialysis and hospitalized patients in order to evaluate the possible usefulness of GDS-15 in hemodialysis patients.

Methods: Thirty-one hospitalized and 31 young-old hemodialysis patients aged 65-74 (young-old) were enrolled in the study. Comprehensive geriatric assessment (Mini Mental State Examination (MMSE), BDI, GDS-15, Cumulative Illness Rating Scale (CIRS) and Activities of Daily Living (ADL)) was made for all patients. The internal consistency between BDI and GDS-15 was evaluated with Cronbach's alpha coefficient. Sensitivity, specificity and receiver operating characteristic (ROC) curves for GDS-15 were determined using BDI as the standard.

Results: In the hospitalized group, the prevalence of depressive symptoms, as evaluated by BDI (> or =14) and GDS-15 (> or =6), were 29 and 32%, respectively. In the hemodialysis group, the prevalence of depressive symptoms, as evaluated by BDI and GDS-15, were 61 and 58%, respectively. A significantly positive correlation between the BDI and GDS-15 was found in hospitalized (r = 0.808; p < 0.001), hemodialysis (r = 0.692; p < 0.001) and both patient groups together (r = 0.777; p < 0.001). The area under the ROC curve was 0.99 in the hospitalized and 0.95 in the hemodialysis groups. The ROC curves indicate a best effectiveness cutoff point (balancing sensitivity and specificity) of > or =6 for GDS-15 compared to BDI.

Conclusions: The GDS-15 could be a useful instrument for evaluating depressive symptoms in young-old hemodialysis patients.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Depression / diagnosis*
  • Depression / etiology
  • Depression / psychology*
  • Female
  • Geriatric Assessment / methods*
  • Humans
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / psychology*
  • Kidney Failure, Chronic / rehabilitation*
  • Male
  • Personality Inventory
  • Renal Dialysis / psychology*
  • Surveys and Questionnaires