Hirudin--the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond. A historical piece

Thromb Haemost. 2007 Jul;98(1):116-9.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Anticoagulants
  • Hirudin Therapy*
  • Hirudins* / chemistry
  • Hirudins* / isolation & purification
  • Hirudins* / pharmacokinetics
  • Humans
  • Leeches
  • Peptides / chemistry
  • Peptides / therapeutic use
  • Recombinant Proteins

Substances

  • Anticoagulants
  • Hirudins
  • Peptides
  • Recombinant Proteins